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Use In Specific Populations 8.1 Pregnancy Risk Summary Based on animal data showing adverse renal effects, XIGDUO XR is not recommended during the second and third trimesters of pregnancy

Excessive consumption of over-the-counter drugs containing paracetamol (eg, antipyretics, analgesics, etc.) can lead to hepatotoxicity and deplete the bodys glutathione system

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Consequently, it is often possible to elute binding partners in an interaction complex without also eluting the biotinylated component

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