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In a mouse model of RP, SOD1 deficiency leads to increased retinal oxidative damage and accelerated loss of cone function through reduced expression of SOD1 and GPx-4 (84)

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The most commonly reported side effects are mild and temporary: Nausea A brief headache Slight dizziness Minor skin sensitivity at the IV site These typically resolve within a few hours without intervention

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Glutathione can exist intracellularly in either an oxidized (glutathione disulfide) or reduced (glutathione) molecular state

Various topical, oral, and injection-based cosmetic skin-lightening agents with different mechanisms of action are used widely across Asia, including hydroquinone, azelaic acid, kojic acid, mulberry, alpha-arbutin, beta-arbutin, glutathione, licorice root, papaya, vitamin A (e.g., retinol), vitamin B (i.e., niacinamide), and vitamin C