The approvals are based on robust clinical trial data demonstrating their efficacy and safety with indications typically targeting a specific BMI category (10, 11, 1927)
They're also a smart starting point if you've overcomplicated your routine and need to calm things down cosmetically while still doing something purposeful for firmness and texture support
Rapid weight loss and reduced food intake deplete these micronutrients, weakening hair resilience

Ipamorelin (INN) (developmental code name NNC 26-0161) is a peptide selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS) and a growth hormone secretagogue.[2][3] It is a pentapeptide with the amino acid sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2 that was derived from GHRP-1.[4] Ipamorelin significantly increases plasma growth hormone (GH).[1][3][5] In addition, ipamorelin stimulates body weight gain in animals.[5] Like pralmorelin and GHRP-6, ipamorelin does not affect prolactin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), or thyroid-stimulating hormone (TSH) levels.[3] However, unlike pralmorelin (GHRP-2) and GHRP-6, but similarly to growth hormone-releasing hormone (GHRH), ipamorelin does not stimulate the secretion of adrenocorticotropic hormone (ACTH) or cortisol, and is highly selective for inducing the secretion only of GH.[3] Ipamorelin Peptide is under active investigation in a number of cell culture and animal models

For split dosing, which maintains the same total weekly dose, mathematical models suggest efficacy maintenance of 80% to 95%
Skincare cannot remove excess loose skin or replace professional treatments where significant loose skin is present