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The vote comes as pharmaceutical giants such as Novo Nordisk and Eli Lilly lower prices on their injectables and a new oral version amid intensifying competition, though monthly costs still reach into the hundreds of dollars
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Key words: tirzepatide-induced liver injury, glucose-dependent insulinotropic polypeptide receptor agonist, glucagon-like peptide-1 receptor agonist Highlights Tirzepatide use for the treatment of type 2 diabetes mellitus, obesity, and obstructive sleep apnea has increased dramatically in recent years Common side effects include gastrointestinal symptoms, which increase at higher doses Serious adverse events were reported in less than 10% of trial participants Recent cases of tirzepatide-induced hepatocellular injury have been reported, presenting a rare but serious complication that is potentially reversible with early recognition Clinical Relevance Tirzepatide-induced liver injury is a serious adverse reaction that can occur despite prior glucagon-like peptide-1 receptor agonist tolerance

Benefits of LixiLan, a titratable fixed-ratio combination of insulin glargine plus lixisenatide, versus insulin glargine and lixisenatide monocomponents in type 2 diabetes inadequately controlled on oral agents: the LixiLan-O randomized trial
While adequate protein intake is important for muscle health, satiety, and overall nutrition, metabolic health cannot be reduced to protein alone