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(Randomized, crossover.) See primary paper: Walker et al., Am J Clin Nutr 2022

A recent discussion from Cedars-Sinai highlights growing interest in whether smaller doses can still support weight loss and metabolic health in selected individuals

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Throughout the manuscript, rejuvenation-oriented terminology has been avoided in favor of functional descriptors that more accurately reflect the current evidence base, including circadian robustness, rhythm amplitude, sleep consolidation, and metabolic alignment

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