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Five-day dosing increases total weekly exposure by approximately 40%

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Semaglutide can be effective for weight loss, but some people may experience side effects as their body adjusts

For Weight Management : It is approved for adults with obesity (BMI 30) or overweight individuals (BMI 27) who also have at least one weight-related health condition, such as high blood pressure, Type 2 diabetes, or high cholesterol

Cardiovascular effects: Phase 2 trial data indicate that retatrutide was associated with modest increases in resting heart rate, consistent with observations seen with other GLP-1 receptor agonists