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This difference was observed in patients on different background therapies as placebo-controlled studies (PIONEER 1, 5, and 8) were conducted in patients receiving semaglutide in addition to diet and exercise, patients with moderate renal impairment using metformin, SU with or without metformin, or basal insulin with or without metformin, and in patients on stable treatment with insulin therapies with or without metformin

Fill up a reusable water bottle and take plenty of drinks to keep your body hydrated until this side effect passes

Arch Dermatol 139:767770 Anavi Y, Mintz S (1992) Unusual physiologic melanin pigmentation of the tongue

To help with side effects when you take semaglutide, you need to drink plenty of water

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