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Epitalon may support sleep-related biological pathways, particularly those connected to pineal function and sleep-wake regulation

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Even though none of the studies found any negative effects of coffee over the risk of DM2, it is also important to highlight that habitual coffee/caffeine consumption have been related to deleterious effects such as bone loss in elderly postmenopausal women, increases in serum homocysteine and cholesterol and blood pressure, as well as risk of coronary heart disease

Hamidi et al., 2023) (see Table 2)