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c , Immunoblot analysis of indicated proteins from Slc33a1- knockout KPK cells expressing a vector control, WT SLC33A1 or disease-associated SLC33A1 variants

Activated macrophages of importance in host pathogen infection by producing inflammatory factors and pro-inflammatory mediators, such as nitric oxide (NO), prostaglandin E2 (PGE2), inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), metalloproteinases, TNF-, interleukin (IL)-1, and IL-6, which recruit more immune cells to the site of infection or tissue damage [[135], [136], [137]]