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Translational potential of differential metabolomics analysis for NPH surgery outcome prediction with additional biofluids To assess whether the molecular signature associated with shunt surgery responsiveness obtained from intraoperative cerebroventricular samples is also reflected in more clinically accessible lumbar CSF or plasma, we analyzed the targeted metabolomics dataset comprising n=56 samples, of which 12 lacked follow-up clinical data

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They serve as the building blocks of important enzymes and hormones