As the total number of studies investigating GLP-1 + cell numbers and function in the context of intestinal inflammation is limited and results are conflicting (26, 27, 3234), we quantified numbers of GLP-1 expressing cells in 4 different mouse models of ileal and colonic inflammation ( Tnf ARE mice (ileitis), IL-10 -/- mice and adoptive T cell-transfer model (colitis) as well as Citrobacter rodentium -infection (colitis))
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Las votaciones no son vinculantes y la FDA peridicamente ha desodo las recomendaciones de sus expertos externos