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This review highlights GSH depletion in brain regions affected by mild cognitive impairment and Alzheimers disease and proposes GSH supplementation as a potential strategy to support cognitive function

Associations between plasma levels of vitamins and cataract in the Italian-American Clinical Trial of Nutritional Supplements and Age-Related Cataract (CTNS): CTNS Report #2

PubMed Central, Shao, Peilu, et al

When I first began working with glutathione, I knew how powerful it could be, but this study confirmed it works because we solved the absorption challenge. Everyday Wellness Applications Why does this matter for everyday health

In one of these studies, measuring brain GSH levels with in vivo proton MRS yielded a correlation in GSH reduction and decline in cognitive functions with 87.5% sensitivity and 100% specificity (Mandal et al., 2015)

Briviba K, Kissner R, Koppenol WH, Sies H