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5-Amino-1-methylquinolinium (5-Amino-1MQ) is a small-molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT) an enzyme linked to metabolic rate regulation, fat storage, and cellular energy balance

It has been investigated as a potential therapeutic for insomnia, depression, and pain conditions

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These approaches expand the experimental toolbox available to researchers probing peptide pharmacokinetics and distribution