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In most cases, you may be able to start your new medication on your regular dosing day, 1 week after your last dose of the old medication

This may also lessen the extent to which astrocytes participate in peripheral immune cell recruitment and inflammation (Mecha et al., 2013)

Peer review Peer review information Nature Communications thanks Martin Steger and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

First-order kinetics are seen in single-compartment models

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Hydration changes appear sooner