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Half-life ~4 hours

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While moderate coffee intake may have some positive effects, excessive caffeine can have the opposite impact

B12 supplements are often used to treat or prevent deficiency, which can lead to symptoms such as fatigue, weakness, constipation, loss of appetite, and megaloblastic anemia

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Several other studies have also provided evidence that GLP-1RA can reduce hepatic fat accumulation and reduce steatosis in liver tissue by regulating the expression of genes and proteins related to the fat synthesis pathway [109,110]