Statistical significance is tested at 5% level, with no correction for multiple testing
That is why screening, monitoring, and dose adjustment are part of every plan
For those with contraindications to, or personal preferences against, using pharmacologic therapies, the following natural supplements have evidence to support their use in managing perimenopausal symptoms: Phytoestrogens , found in soy, beans, flax seeds, and cruciferous vegetables, are plant compounds that may support the reduction of menopausal symptoms (5)
They are transferred to extrahepatic tissues and organs, such as brain and heart as substitute fuels [119, 120]
Davis and S
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