semaglutide heart rate increase Glucagon-like peptide-1 increases by a direct action on the sinus node How Semaglutide Improves Blood Pressure

That appetite reduction is a big reason GLP-1 agonists lead to weight loss

Once transformed, diploid hepatocytes tend to proliferate extensively, driving tumor growth [17]

Some studies indicate GLP-1s may reduce the risk of substance use disorders (Nature Medicine), neurocognitive disorders (including Alzheimers disease), infectious diseases, some respiratory conditions and certain cancers (JAMA Oncology)

[15] Tirzepatide also delays gastric emptying, and the same NSAID interaction logic applies

At 52 weeks: For patients not using PAP therapy, tirzepatide reduced AHI by 25.3 events/hour compared to just 5.3 with placebo

Everything below is reasonable extrapolation from constipation, IBS, and general population research, not a head-to-head study in people on these drugs