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3-AR is specific to adipose tissue (unlike 1 and 2, which are in the heart and lungs)

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The condition is largely associated with obesity and an unhealthy diet and lifestyle, and is on the rise in industrialised nations

Il joue galement un rle cl dans plusieurs voies enzymatiques impliques dans le mtabolisme et llimination de certaines substances, confirmant sa place centrale dans le fonctionnement cellulaire normal