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Dihydroartemisinin triggers ferroptosis in primary liver cancer cells by promoting and unfolded protein responseinduced upregulation of CHAC1 expression

Crcep 16

PubMed USADA

ROS and RNS production are facilitated by pattern recognition receptors [C-reactive protein (CRP), toll-like receptors] capable of recognizing pathogen (bacterial/viral)-associated molecular patterns and/or damage-associated molecular patterns in apoptotic or damaged cells (92100) (Figure 6)