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GIPR activation, shown in orange, primarily targets adipose tissue and the pancreas

Pain Relief 1 , 109 (2012)

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Carcinogenesis In a 104-week carcinogenicity study in rats at dose levels of 2, 20, 60, or 80 mg/kg/day by oral gavage, the incidence of uterine stromal polyps was significantly increased in females at 80 mg/kg/day at systemic exposure 20 times the human exposure at 40 mg/day based on AUC

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As Chris explains: I first started using L-Carnitine in 2011/2012.This coincided with a big step up in Ironman performance from top ten age-group athlete to top ten overall in big Ironman races