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The volume of BAC water added decides the final concentration in mg/mL, which in turn decides the syringe draw volume for any target dose

For most healthy adults, the clinical trials at common doses do not demonstrate clear, proven harms, but the TMAO question remains an area of active research

A commonly used regimen is a loading phase of 25 mg per week (subcutaneous injection) for 46 weeks, followed by a maintenance dose of around 2 mg every 12 weeks

Rates of serious adverse events were similar between the intervention group and placebo group (10% vs 8.1%)

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I 2 = 0%), or vomiting (OR: 8.22, 95% CI: 4.02, 16.81