glp-1 effect on muscle mass loss and GLP-1R agonists use | Acta Diabetologica How to Prevent Muscle Loss

33 de Almeida LM , Azevedo RS , Marandino Guimares AA , da Silva Freire Coutinho E , Struchiner CJ , Massad E

They had very similar findings, where they saw that about 80% of their patients were taking [GLP-1s] for diabetes indications, and the weight loss ranged in the 2% to 3% range, [which] is even more modest than what we would expect

Statements Author contributions RA-T: Conceptualization, Investigation, Writing original draft, Writing review & editing

This rebound is not a side effect of the drug but a natural result of going back to old habits without the appetite-controlling support of the medicine

Healthcare providers should consider this limited evidence base when making treatment decisions and should discuss these limitations with patients

2) subscription-style treatment payments at a predictable per-member cost;11 3) outcome-linked, annuitised payments;12 and 4) collective, evidence-based price negotiations for new therapeutics