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Alternative medication classes for diabetes (such as SGLT2 inhibitors) or weight management should be considered, recognizing that heart rate increases can occur with other GLP-1 receptor agonists as well

Patients taking multiple medications for diabetes should work closely with their healthcare provider to optimize the overall regimen, as dose adjustments of other agents may be necessary as these medications take effect

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According to Apovian, the drugs can be made in different countries without the same safety and manufacturing requirements that are required for FDA-approved drugs

For instance, a study in Lancet reported that individuals taking semaglutide achieved substantial weight loss compared to those not using the medication