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[45] Ten milligrams at 200% DV is well above the 5mg adequate intake and is well-tolerated with no established upper limit

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they are not FDA-approved drugs and require ongoing clinical oversight and patient responsibility

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The company was cleared to manufacture and market a once-weekly injectable treatment for adults whose type 2 diabetes is not adequately controlled

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UT Southwestern recommends that patients with obesity work with an obesity specialist along with their Ob/Gyn before, during, and after pregnancy to reduce potential risks and increase the chances for a healthy pregnancy

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Results from a phase 1 trial have supported further clinical evaluation with a dose-dependent WL up to 14.5% with AMG133 compared to 1.5% with placebo by day 85 [59]

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For patients who are hesitant about injections, the convenience of a daily pill lowers barriers to starting and staying on the medication long-term

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