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High-fat, greasy foods are particularly problematic

Some combination of coaching or nutritionist support increases outcomes

This means semaglutide does the same job as a hormone your gut makes

Evidence-based strategies include increasing protein intake to meet individual needs, emphasizing high-fiber foods (aiming for 2530 g daily per Dietary Guidelines for Americans), and minimizing ultra-processed foods to help stabilize blood glucose and prolong fullness

Dunnetts post-hoc tests were performed for specifically comparing agonist responses with exendin-4, and Tukeys for differences between all groups

Hypoglycemia occurred in 0.5% to 0.6% of semaglutide patients and 0 to 1.1% of placebo patients in the STEP 1, STEP 3, and STEP 4 studies, while in the STEP 2 study, where patients also had type 2 diabetes, they occurred in 6% of semaglutide patients and 3% of placebo patients