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While ATP could be added exogenously, tissue penetration and unintentional activation of purine receptors are concerns

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The CTG assay showed that RNK06138 reduces the viability of MOLP-8 (IC 50 = 98.39 nM), MDA-MB-231 (IC 50 = 190 nM), Huh-7 (IC 50 = 110.15 nM), A427 (IC 50 = 83.04 nM), JHH-7 (IC 50 = 142.44 nM), and A375 cells (IC 50 = 60.23 nM) (Fig

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