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The evidence that any specific formulation carries a different safety profile is limited

Category 2 Key clinical evidence Sermorelin FDA-era pediatric trials + PK data Tesamorelin Phase 3 visceral fat data CJC-1295 (DAC) Phase 1 PK and GH/IGF-1 duration data Typical research dose Sermorelin 200-300 mcg nightly Tesamorelin 2 mg daily CJC-1295 (DAC) 1-2 mg weekly Main use case Sermorelin GH optimization, sleep, recovery Tesamorelin Visceral fat / metabolic context CJC-1295 (DAC) Sustained GH/IGF-1 elevation All three target the same receptor but are not interchangeable

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