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The study conducted in MadinDarby canine kidney cells depicted that the prepared NPs were effectively taken by the body via multiple nonspecific mechanisms including clathrin-mediated endocytosis, micropinocytosis, and caveolae/lipid raft-mediated endocytosis
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[DOI] [PMC free article] [PubMed] [Google Scholar] [76].Hoshida S, Kuzuya T, Yamashita N, Nishida M, Kitahara S, Hori M, Kamada T, Tada M
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Research has examined BPC-157 and TB-500 both individually and in combination across wound healing, musculoskeletal repair, and neuroregeneration models , with combination studies characterising whether the two peptides produce additive or synergistic effects on repair endpoints that exceed those of either peptide alone, and examining the mechanistic basis for any enhanced effects observed with the combination relative to monotherapy