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Docking studies revealed that the most active compounds formed strong binding interactions, and the overall energy scores supported the impressive COX-2 inhibitory activity observed

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The MGF E-peptide has been shown to significantly increase the proliferative lifespan and delay senescence of satellite cells isolated from neonatal and young adult human muscle, while having attenuated effects in cells from older adults establishing an age-dependent satellite cell responsiveness to MGF that underpins its utility as a sarcopenia and muscle ageing research tool

Funding DH is funded by grants from the Natural Sciences and Engineering Research Council of Canada (Grant No

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