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HbA1c measures the average blood sugar levels over the past three months, corresponding to the average lifespan of red blood cells (RBCs) and indicating the extent to which the RBCs are "sugar-coated." For reference, the American Diabetes Association (ADA) advises that the target A1C for most adults with diabetes should be below 7%

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Preterm infants frequently encounter metabolic stressors such as hypoxia and infection

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The FDA adds a buffer to that, giving the two-month recommendation its practical basis