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Oral versions of dual agonists are in development

Which gets us to our final point

Reagent 2

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These clinical observations argue that preclinical testing of hydrogel-based radiosensitizers must explicitly compare SCC and AC modelsincluding cell lines, patient-derived xenografts (PDX), and organoidsto define whether particular payloads (e.g., oxygen carriers, platinum agents, STING agonists, or specific nanoparticles) preferentially resensitize one histology over another [185]