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In a 26-week rat oral toxicity study, AOD-9604 produced dose-dependent changes in serum osteocalcin (a bone-turnover marker) at week 13, with the direction reversing by week 26

These generally show continued safety, but definitive long-term studies don't exist

For people with an MTHFR mutation, methylcobalamin (as opposed to other forms of B12) is therapeutic

Pushing it too hard with an intense workout might leave you feeling depleted instead of revitalized

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