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Glutathione has been shown to reduce oxidative stress and damage in people with uncontrolled diabetes, despite high sugar levels

Abbreviations BBB: Blood-brain barrier BER: Berberine CS: Chitosan DMSO: Dimethyl sulfoxide EE %: Percentage entrapment efficiency GFAB: Glial fibrillary acid protein GSH: Reduced glutathione IHC: Immunohistochemistry MAO-B: Monoamine oxidase B MPTP/P: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine PDI: Polydispersity index PD: Parkinsons disease SOD: Superoxide dismutase TEM: Transmission electron microscopy TNF-: Tumor necrosis factor alpha References Cheng Z, Kang C, Che S, Su J, Sun Q, Ge T, Guo Y, Lv J, Sun Z, Yang W, Li B, Li X, Cui R

Ley RE, Turnbaugh PJ, Klein S, Gordon JI

Somatic mitochondrial DNA mutations in cortex and s ubstantia nigra in aging and Parkinson's disease

This imbalance of more free radicals than antioxidants is known as oxidative stress and has been associated with numerous health problems

however, its clinical application was limited by adverse effects including pulmonary complications and anemia 77 (Fig