Both compounds not only combat oxidative stress but also promote overall skin vitality
doi: 10.1080/23311932.2023.2226427
2.3.1 Negative regulatory factors of System Xc - Inhibiting cysteine uptake by System Xc - can inhibit the synthesis of GSH, leading to the accumulation of peroxides in the body and the induction of ferroptosis (64)
Furthermore, it was demonstrated that pharmacological stabilization of cardiolipin, a key lipid in the mitochondrial membrane, can reverse the energy dysfunction observed in vitiligo melanocytes, which suggests that manipulating cardiolipin could be a promising new therapeutic strategy for treating vitiligo.43 Vitiligo skin shows morphological changes in the epithelium and in the upper dermis
Sun M, Sang Y, Deng Q, Liu Z, Ren J, Qu X
Kern JK, Geier DA, Adams JB, et al