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Glutathione peroxidase 4 (Gpx4) and ferroptosis: what's so special about it

doi:10.2337/diabetes.42.11.1678

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Once the oxidative threat has passed and the cellular redox balance is restored, specialized enzymes such as glutaredoxin (Grx) or thioredoxin (Trx) carefully remove the glutathione cap, returning the protein to its normal, functional state