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PMID 29119245

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It targets three key hormone receptors at the same time: GLP-1 (glucagon-like peptide-1) Stimulates insulin release Reduces glucagon secretion Helps regulate blood sugar GIP (glucose-dependent insulinotropic polypeptide) Enhances insulin response Improves insulin sensitivity Glucagon Receptors Increases energy expenditure Promotes satiety and appetite control This triagonist design offers a multifaceted attack on metabolic dysfunction, addressing blood sugar, appetite, and energy usage all at once

So theyre essentially just playing a numbers game

- GLP-1 and GLP-1 receptor agonists (GLP-1 RAs) have protective effects in stroke models