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Provider oversight is essential to rule out contraindications and monitor response

If darkening appears quickly or spreads rapidly, consult a healthcare provider promptly

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Results represent participants receiving the 12mg maintenance dose over 68 weeks

GLP-1s are prescribed to adults with a BMI over 30, or adults with a BMI over 27 who also have obesity-related conditions, such as prediabetes, diabetes, high blood pressure, high cholesterol, sleep apnea, and fatty liver disease

Cells take it up and convert it to ZMP, an AMP analogue that activates AMP-activated protein kinase (AMPK), the cell's master fuel gauge