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The discovery that NNMT expression is dramatically elevated in adipose tissue of obese humans and animal models, and that NNMT inhibition or knockdown prevents diet-induced obesity and improves metabolic health, has catalyzed intense research interest in NNMT as a therapeutic target for obesity, metabolic syndrome, and related conditions

That said interest does not equal proof

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Biocompatibility: AHK-Cu is biocompatible, meaning it is well-tolerated by the human body and does not cause adverse reactions

When switched on, AMPK has a number of downstream effects

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