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Even more, crizotinib (c-MET inhibitor) and gefitinib given in combination potentiated the effects of cell line invasion, wound healing, and proliferation

approval in 2005

Green R, et al

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It also suppressed NF-B p65 and p38 MAPK signaling pathways and protected the lungs by reducing reactive oxygen species (ROS) production, stimulating superoxide dismutase (SOD), while decreasing TNF- and IL-6 production [ 46 ]

Why are they sold as a blend