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and 2) the need to be manufactured by recombinant methods at high cost, thus limiting its widespread use

While adverse effects are rare, users should remain aware of potential issues and understand the limitations of current research

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A study generated a new suicide gene/prodrug system showed that specific cancer cells modified to express Tb HGPRT were able to convert the non-toxic allopurinol into cytotoxic metabolites, selectively induced apoptosis in five NSCLC cell lines, one murine lung cancer cell line (M27), and four human NSCLC cell lines (A549, H460, H661, H520)

Hashimoto's encephalopathy associated with an elevated intrathecal IgG4 level

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