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Nitric oxide (NO) is nitrogen based-reactive species and as membrane permeable radical can react with superoxide to form peroxynitrite, an agent with oxidizing and nitrating properties [48]

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For instance, peptides containing methionine are more likely to oxidize, while those with asparagine might undergo deamidation

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Retatrutide and tirzepatide are typically supplied at higher concentrations than 1 mg/ml after reconstitution, so the unit math is different from semaglutide