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Once this endpoint was reached, mice were immediately removed from the ether chamber and placed in a recovery cage under continuous observation until they regained consciousness

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Additionally, ROS can influence the differentiation and function of T cells, promoting the polarization of T helper 17 (Th17) cells, which are known to play a pathogenic role in autoimmune diseases such as multiple sclerosis (MS) and psoriasis [136]

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Therefore, Gln deficiency has led to immune dysfunction and HA overproduction in people at high risk of COVID-19