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Keywords: glutathione, meta-analysis, randomized controlled trial, Parkinson's disease Introduction Parkinson's disease (PD) is a progressive neurodegenerative disease associated with aging, which is characterized by the selective loss of nigrostriatal dopaminergic neurons (1-3)

The importance of selenocysteine comes from its role in gene expression and activity of the Se-dependent enzyme, GSH-Px (Floh et al., 1997

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Whilst B12 plays an essential role in energy metabolism, red blood cell production, and nervous system function, there is no evidence that supplementation increases energy in individuals with normal B12 status

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The briefing materials also noted that it is unclear whether these AEs were attributable to BPC-157