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PHQ-9, Patient health questionnaire-9

The thiol group of glutathione chelates copper ions on the active site of enzyme tyrosinase thus inhibiting it

| Concentration | BAC Water | Doses at 1.0mg | Doses at 2.4mg | |---------------|-----------|----------------|----------------| | 5mg/mL | 2.0mL | 10 doses | ~4 doses | | 2.5mg/mL | 4.0mL | 10 doses | ~4 doses | **Best practice:** 2.0mL BAC water gives a clean 5mg/mL concentration

However, the role of p53 in regulation of IGF-1R seems to be more complex and probably also involves post-transcriptional mechanisms (Girnita et al, 2000

Use of other drugs - While drug use will not affect BAC, it could mask the effect of alcohol