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Lonicera japonica is indigenous to China and enjoys a broad distribution across East Asia, including regions such as Japan and the Korean Peninsula (33)

It seems to be the most effective MAPK, in stabilising, at post-transcriptional level, the mRNAs for cytokines and chemokines relevant to COPD pathogenesis

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[1] It binds copper ions and hands them to copper-using enzymes needed for collagen cross-linking (lysyl oxidase) and antioxidant defense (SOD)