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The most common systemic side effects nausea, vomiting, diarrhea come from the medication itself, not from injection technique, and tend to be strongest in the first weeks or after a dose increase

This highlights the necessity of preserving or increasing MM during weight loss to limit metabolic slowdown, prevent plateaus, and reduce the risk of weight regain

The FDA is being cautious about allowing distribution of a compound without comprehensive safety data

Weekly injections: Compounded semaglutide

Semaglutide GLP-1 option commonly associated with Wegovy, Ozempic, and Rybelsus

Semaglutide also carries a boxed warning about thyroid C-cell tumors occurring in rodents (with unknown risk in humans)