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Additional risk factors include: Chronic kidney disease : Reduced renal clearance may impair B12 excretion Liver disease : Hepatic dysfunction can disrupt B12 metabolism and storage Myeloproliferative disorders : Certain blood cancers increase B12-binding proteins Concurrent medication use : Some drugs may interact with B12 metabolism, including metformin, proton pump inhibitors, and H2 antagonists Patients with these conditions should have B12 supplementation carefully monitored by their healthcare team

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These people would otherwise rely on the availability of daily B12 shots to counter their inability to absorb B12 through the gut

This medication helps reduce the discomfort and decrease food intake, making it easier for patients to maintain healthy eating habits and achieve long-term results