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CONCLUSION Under a collaborative approach to treating cleft lip and/or palate, the role of the dental team has become more prominent with the rise of PSIO but the importance of the dental provider remains integral over time

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Data Sharing Statement All data generated or analyzed during this study are included in this published article

The use of biocompatible delivery materials, such as polymer NPs and liposomes, is recommended to mitigate potential side effects

Reliable quantification of individual NAD metabolites and glutathione can be achieved through liquid-chromatography mass-spectrometry (LC-MS) 22 , cyclic enzymatic assays and high-performance liquid chromatography (HPLC) 2326 , but these have not been applicable for the scalable analysis of the whole redox set, especially from a single extract

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