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In senescent cells, however, p53 is actively suppressed by the transcription factor FOXO4

Half the intended dose, for the entire cycle

54, 55, 56 Interestingly, one of the claudin family proteins, claudin-7, when expressed in intestinal epithelium demonstrates a prominent basolateral membrane distribution compared with other claudins that localize primarily to the apical TJs in the intestinal epithelium

The most frequently encountered are 5 mg, 10 mg, 15 mg, and 30 mg vials