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Vitamin B12, also known as cobalamin, is a water-soluble vitamin that plays an essential role in supporting nerve function, red blood cell formation, DNA synthesis, and energy metabolism

Clinicians estimate vitamin B12 requirements using values such as: Recommended dietary allowance (RDA): RDArefers Trusted Source National Institutes of Health Office of Dietary Supplements Go to sourceto a daily intake that, on average, is enough to meet the nutritional requirements of almost all people without underlying health conditions

The Babula 2024 mouse study saw clear fat-mass reduction at 28 days, which scales roughly to 610 weeks in humans

The Forms at a Glance Vitamin B12 exists in several molecular forms

Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice

The Short-Term Timeline: Days 3 to 7 By the end of the first week, the initial surge settles into a steadier supply of B12, and this is often when the more noticeable day-to-day changes appear